Love X Holic Miwaku No Otome To Hakudaku Kankei The Animation

Based on the erotic game by Atelier Kaguya Bare & Bunny. In a world where humans and demi-humans coexist, Taichi Amano has by accident drank some blood of Kuon Aoe, the most popular girl in the school. Drinking her blood changed his body to have a special constitution which awakens demi-humans. In exchange for protecting Taichi from whoever would target him, the Aoe house made him cooperate with awakening Kuon... (Source: VNDB)